Keywords
Anti-bacterial activity
MIC and MBC
How to Cite
Abstract
Protein was extracted from muscles of Channa striatus and attempts were made to evaluate in vitro antibacterial activity against clinical bacterial isolates. The higher concentration of protein (100μg/ml) extracts exhibited a pronounced activity against Pseudomonas aeruginosa (21 mm), Proteus vulgaris (19 mm), Citrobacter sp (19 mm), Klebsiella pneumoniae (18 mm), Micrococcus sp (17 mm), Bacillus subtilis (16 mm), Staphylococcus aureus (15 mm), E. coli (14 mm) and Serratia marcescens (5 mm). The minimum inhibitory concentration and minimum bactericidal concentration were found to be 20-40 μg/ml and 80-100 μg/ml respectively for the extracts of Channa striatus protein against test organisms. This study confirms that C. striatus fish protein extracts possess antibacterial activity against a wide range of microbes and justified that it could be used in the traditional medicine as a remedy for the treatment of bacterial diseases.
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