Antiulcer activity of Property fruit extract of the Cucumis trigonus L. In albino rats
Abstract
The effect of alcoholic fruit extract of Cucumis trigonus L. (Family: Cucurbitaceae) was evaluated for the anti-ulcerogenic activity with aspirin induced ulceration in albino rats and various biochemical parameters viz., ulcer index, mucus production, total volume of gastric juice, pH of gastric juice were analyzed. A qualitative phyto chemical analysis was carried out and the fruit extract was found rich in carbohydrates, flavonoids, fixed oils and fats. Although the fruit extract of all the concentrations were active in reducing the gastric acidity, the drug dosage at 400 mg/animal was found as the most effective in anti ulcer activity. The presence of flavonoids in the alcoholic fruit extract of the plant is being the responsible for their antiulcer properties.
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