Studies on phytochemicals, antibacterial and Antioxidant effects of leaf extracts of Lamprachaenium microcephalum
Abstract
In this investigation, Lamprachaenium microcephalum was analysed for its phytochemical constituents qualitatively and quantitatively. The antibacterial property of aqueous, ethanolic and hexane extracts of Lamprachaenium microcephalum was studied against different bacteria include Escherichia coli, Proteus mirabilis, Salmonella typhi, Enterobacter aerogenes, and Shigella flexineri and showed growth inhibition activity at concentrations in the range of 300mg to 500mg. The antioxidant effect of those extracts was also studied against α-tocopherol as a control. From the results, Alkaloids, flavonoids, saponins, and tannins were revealed to be present in Lamprachaenium microcephalum. Ethanol extract at the concentration of 500μg/ml showed 61.16% antioxidant activity against 500 μg/ml of α-tocopherol which showed 76.86% as a standard reference
References
Ali Yildirim, Manir Oktay, Vahit bilaloglu. 2001. The antioxidant activity of the leaves of Cydonia vulganis. Tr. J. Med. Sci., 31:23-27.
Burlon GW and Ingold KU. 1984. B-Carotene, an unusual type of lipid antioxidant. J. Sci., 224:573.
Chung KT, Thomasson WR and Wu-Yuan CD. 1990. Growth inhibition of selected food-borne bacteria, particularly Listeria monocytogenes, by plant extracts. J. Appl. Bacteriol., 69:498-503.
Donald RB and Cristobal M. 2006. Antioxidant activities of flavonoids, J. Agric., 52:125-757.
Gurudeva MR and Yoganarasimhan S. Bibliography of Medicinal plants of India (Pharmacognosy and Pharmacology), 2009, Divyachandra Prakashana, Bangalore. 621-622, 703-712.
Harborne JB. 1973. Textbook of phytochemical methods, 1st Edn, Champraan and Hall Ltd. London. 110-113.
Harborne JB. 1976. Phytochemical methods, Second Edition, Chapman and Hall Ltd, London. 52-55.
Hoffman BR, Delas Atlas H, Blanco K, Wiederhold N, Lewis RE, Williams L. 2004. Screening of antibacterial and antifungal activities of ten medicinal plants from Ghana. J. Pharm. Biol. 1(42): 13-17.
Matook Sait Mokbel. 2005. Hashinaga. Antioxidant activities of Banana (Musa AAA cv. Cavendish) fruits peel. Am. J. Biochem.Biotechnol., 1(3):126-132.
Mistuda H, Yuasumoto K, Iwami. 1996. Antioxidation action of Indole compounds during the autoxidation of linoliec acid. Nihon Eiyo Shokuryo Gakkai-Shi., 19:210-214.
Odebiyi OO and Sofowora EA. 1979. Phytochemical screening of Nigerian Medicinal plants 2nd OAU/STRC Inter-African Symposium on traditional Phamacopoeia and African Medicinal 216-220.
Oloyed OI. 2005. Chemical profile of unripe pulp of Carica pagaya. Pak. J. Nutr., 4:379-381.
Onwuka GI. 2005. Food Analysis and Instrumentation theory and Paractice, 1st Edn, Naphthali prints, Lagos.114-169.
Palozza P. 1998. Pro-oxidant actions of Carotenoids in Biologic Systems. Nutr. Revolution 56:257-256.
Sofowora EA. 1983. Proceedings of the 5th International Symposium on medicinal plants. University of Ile-Ife, Nigeria. 7.
Shobana S, Vidhya VG and Ramya M. 2009. Antibacterial Activity of Garlic Varieties (Ophioscordon and Sativum) on Enteric Pathogens, Curr. Res. J. Biol. Sci., 1(3):123-126.
Tanaka JCA, Da Silva CC, De Oliveira AJB, Nakamura C, Dias Filho BP. 2006. Antibacterial activity of iodole alkaloids from Aspidosperma ramifloram. Br. J. Med. Biol. Res., 39(3):387-391.
Trease GE and Evans WC. 1989. Pharmacognosy. 2nd Edn, Braille Tiridel and Macmillan publishers.
